Arrhythmias & electrophysiology
Causes of Early Mortality After Ventricular Tachycardia Ablation in Patients With Reduced Ejection Fraction
Authors' conclusion
The overall early mortality (≤30 days) rate after catheter ablation of VT in patients with reduced LVEF was 5.0%, but the death rate directly due to a procedural complication was only 0.4%. The most common cause of death was recurrent VT, followed by heart failure.
Study context
- Population
- Patients with reduced left ventricular ejection fraction (LVEF) (<50%) undergoing ventricular tachycardia (VT) ablation at the Mayo Clinic (Rochester, Phoenix, Jacksonville), 2013–2021
- Participants
- 503 patients
- Outcome
- Early (≤30 days) mortality and its causes after VT ablation
- Follow-up
- ≤30 days
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
30 days
- 30-day all-cause mortality (n = 25)
- 5.0%
- Mortality due to procedural complication
- 0.4%
- Recurrent VT as primary cause, among 30-day deaths
- 44.0%
- Decompensated HF as cause, among 30-day deaths
- 28.0%
- Procedure-related death, among 30-day deaths
- 8.0%
- Cerebrovascular accident, among 30-day deaths
- 4.0%
- Infection, among 30-day deaths
- 4.0%
Observational data: associations, not effects.
Further findings
VT recurrence timing among VT deaths
- VT recurrence within 3 days of ablation among those who died from VT
- 91.0%
PAINESD score among early deaths
- Average PAINESD score (±)
- 20 ± 4
- Score >15 (n = 23)
- 92.0%
Predictors of early mortality
- Significant predictors: nonischemic cardiomyopathy, lower LVEF, electrical storm, VF
Original publication
Causes of Early Mortality After Ventricular Tachycardia Ablation in Patients With Reduced Ejection Fraction. JACC Clin Electrophysiol. Published 31 October 2022. doi:10.
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