Heart failure & cardiomyopathies
Changes Over Time in Patient-Reported Outcomes in Patients with Heart Failure
Authors' conclusion
In total, 79% of the patients with HF encountered problems related to sleep, depressive symptoms, HrQoL, and well-being at least once during a 1-year period.
Study context
- Population
- Patients with heart failure (HF) (mean age 67 years; 29% female, 60% NYHA II)
- Participants
- 603 patients
- Primary endpoint
- Trajectory of four PROs: sleep, depressive symptoms, HrQoL and well-being
- Follow-up
- 1 year (baseline, 3, 6 and 12 months)
Primary result
As reported in the abstract
PROs over 1 year · 12 months
- Good PRO scores at all timepoints
- 21%
- Consistently poor sleep over 12 months
- 17%
- Sustained depressive symptoms over 12 months
- 17%
- Consistently poor health-related quality of life (HrQoL) over 12 months
- 15%
- Poor well-being over 12 months
- 13%
- At least one problem in any PRO during 1 year
- 79%
Further findings
Patient-reported outcomes (PROs) between baseline and 3 months
- Continuing poor sleep
- 16%
- Sustained depressive symptoms
- 11%
- Consistent poor HrQoL
- 13%
- Consistent poor well-being
- 13%
Patient characteristics associated with poor PROs over 12 months
- Age, education, NYHA class and length of disease related to two PRO domains
- 6-min submaximal exercise capacity, co-morbidity and poor physical activity related to one PRO domain
Original publication
Changes Over Time in Patient-Reported Outcomes in Patients with Heart Failure. ESC Heart Fail. Published 29 December 2023. doi:10.
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