Heart failure & cardiomyopathies

Effect of Constipation on Readmission for Heart Failure in Patients with Acute Heart Failure

ESC Heart FailPublished Cohort study

Main finding · Readmission due to HFResult — go to the resultHazard ratio 2.61 95% CI 1.38–4.94

Authors' conclusion

Constipation status was strongly associated with a higher risk of readmission for heart failure in patients with acute heart failure.

Study context

Population
Patients admitted with acute HF, December 2020 to December 2022 (mean age 81 ± 13 years; 54% men)
Participants
397 patients
Exposure
Constipation vs no constipation
Outcome
Readmission due to HF
Follow-up
Median 173 days
Methodological detailssingle-centre, propensity-score matched, 35 patients died and 74 were readmitted due to HF during follow-up
  • Single-centre
  • Propensity-score matched
  • 35 patients died and 74 were readmitted due to HF during follow-up

Main finding

As reported in the abstract

Hazard ratio

2.61

95% CI 1.38–4.94

P = 0.0032

Constipationvs No constipation
HR 2.61 (95% CI 1.38–4.94); P = 0.0032
Higher risk with constipation, Kaplan-Meier before propensity score matching
log-rank P = 0.014
Higher risk with constipation, Kaplan-Meier after propensity score matching (14 variables)
log-rank P = 0.0027

Observational data: associations, not effects.

Further findings

OutcomeHR (95% CI)P value
All-cause death1.76 (0.61–5.06)P = 0.30

Original publication

Effect of Constipation on Readmission for Heart Failure in Patients with Acute Heart Failure. ESC Heart Fail. Published 29 December 2023. doi:10.1002/ehf2.14650

Composed by AI from the published abstract and checked against it. How Briefs are made →

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