Heart failure & cardiomyopathies
Changing patterns of heart failure in China from 1990 to 2021: a secondary analysis of the global burden of disease study 2021
Authors' conclusion
The burden and risk of HF in China remains a major concern.
Study context
- Population
- Population of China with heart failure (HF), 1990–2021
- Primary endpoint
- Prevalence and YLDs of HF
- Follow-up
- 1990–2021
Methodological detailsjoinpoint regression, age-period-cohort model, autoregressive integrated moving average (ARIMA) projection
- Joinpoint regression
- Age-period-cohort model
- ARIMA projection
Primary result
As reported in the abstract
2021
Individuals living with HF
13 099 727
95% UI 11 320 895 to 15 376 467
Years lived with disability (YLDs) due to HF
1 290 810
95% UI 865 894 to 1 775 731
AAPC, age-standardised prevalence rate
0.23%
95% CI 0.20 to 0.26
AAPC, age-standardised YLD rate
0.25%
95% CI 0.23 to 0.27
Further findings
Age-period-cohort analysis
- Local drift curve showed a downward trend with age
- Period and cohort rate ratios increased significantly over the last 30 years
Projected age-standardised rates (ARIMA) · 2031
- Prevalence rate will decrease to
- 678.69 (95% CI 640.75 to 716.63)
- YLD rate will increase to
- 69.19 (95% CI 66.95 to 71.43)
Original publication
Changing patterns of heart failure in China from 1990 to 2021: a secondary analysis of the global burden of disease study 2021. Eur Heart J Qual Care Clin Outcomes. Published 11 July 2025. doi:10. 1093/ ehjqcco/ qcaf064
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