Heart failure & cardiomyopathiesResearch article
Global, Regional, and National Burden of Myocarditis and Its Impairment, 1990-2023
- Systematic analysis of the Global Burden of Disease Study 2023
- age-standardized rates
- stratified by age, sex and Socio-demographic Index (SDI) quintile
Authors' conclusion
Although age-adjusted DALYs and mortality rates of myocarditis decreased globally from 1990 to 2023, incidence and prevalence remained stable, suggesting potential improvements in outcomes over time. However, absolute burden has grown due to population growth and aging, and important disparities persist across age groups and SDI strata.
Study context
- Population
- Myocarditis burden in every country, 1990–2023
- Outcome
- Myocarditis prevalence, incidence, DALYs, mortality and mortality-to-incidence ratio (MIR)
- Follow-up
- 1990–2023
Main finding
As reported in the abstract
Prevalence per 100,000
4.84 (95% UI 3.98-5.80)
Incidence per 100,000
12.46 (95% UI 9.86-15.70)
DALY per 100,000
8.41 (95% UI 5.63-12.59)
Mortality per 100,000
0.21 (95% UI 0.14-0.29)
Further findings
Trends 1990–2023
- Absolute incident cases increased
- 54.28%
- Incident cases 1990
- 0.67 million (95% UI 0.52-0.85 million)
- Incident cases 2023
- 1.04 million (95% UI 0.83-1.32 million)
- Age-standardized disability-adjusted life years (DALYs) decreased
- 62.48%
- Age-standardized mortality rates decreased
- 60.00%
- Global age-standardized prevalence and incidence rates stable
MIR by age · 1990–2023
- MIR <5 years, 1990
- 17.82%
- MIR <5 years, 2023
- 6.32%
- MIR decreased across all age groups; highest in youngest and oldest
By SDI quintile · 1990–2023
- MIR 1990
- 2.33
- MIR 2023
- 1.30
- Prevalence 2023, high SDI per 100,000
- 6.30 (95% UI 5.15-7.48)
- Prevalence 2023, low-middle SDI
- 4.10 (95% UI 3.38-5.02)
- Incidence rates stable; mortality declined in all quintiles, lowest in high SDI
Age-standardized prevalence of HF attributable to myocarditis per 100,000 · 1990–2023
- 1990
- 2.33 (95% UI 1.90-2.90)
- 2023
- 1.76 (95% UI 1.41-2.29)
- U-shaped by age; highest <5 and >75 years in 2023
Original publication
Summarised from the published abstract; every number is checked against it