Acute cardiac care & resuscitation

Characteristics and clinical assessment of unexplained sudden cardiac arrest in the real-world setting: focus on idiopathic ventricular fibrillation

Eur Heart JPublished Prospective registry-based observational study

Authors' conclusion

Our findings suggest that complete investigations are carried out in a very low proportion of unexplained SCA.

Study context

Population
Survivors of unexplained cardiac sudden cardiac arrests (SCA) after OHCA, Paris area, 2011–201688 unexplained after ECG, echo, angiography
Participants
717 survivors
Outcome
Completeness of assessment of unexplained SCA
Methodological detailspopulation-based, Paris area
  • Population-based
  • Paris area

Main finding

As reported in the abstract

Complete workup (incl. pharmacological testing) among IVF

Labelled idiopathic ventricular fibrillation (IVF)

49

6.8%

IVF with complete workup

8

16.3%

Diagnosis by CMR

25

3.5%

Diagnosis by other investigations

14

2.4%

Observational data: associations, not effects.

Further findings

Predictors of more thorough investigation

OR (95% CI)
Younger patients6.00 (1.80–22.26)
University centres3.60 (1.12–12.45)

Genetic testing and family screening initiated (IVF)

Genetic testing
9 (18.4%)
Family screening
12 (24.5%)

Original publication

Characteristics and clinical assessment of unexplained sudden cardiac arrest in the real-world setting: focus on idiopathic ventricular fibrillation. Eur Heart J. Published 16 March 2018. doi:10.1093/eurheartj/ehy098

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