Acute cardiac care & resuscitation

Impact of Bystander Automated External Defibrillator Use on Survival and Functional Outcomes in Shockable Observed Public Cardiac Arrests

CirculationPublished Prospective cohort study

Main findingResult — go to the resultOdds ratio 2.73 95% CI 2.17–3.44

Authors' conclusion

Bystander automated external defibrillator use before emergency medical services arrival in shockable observed public OHCA was associated with better survival and functional outcomes.

Study context

Population
Shockable observed public out-of-hospital cardiac arrest (OHCA), Resuscitation Outcomes Consortium, 2011–2015shockable of 4115 analysed
Participants
2,500 participants
Exposure
Bystander AED shock vs initial defibrillation by EMS
Outcome
Discharge with favorable functional status (modified Rankin Score ≤2)
Follow-up
Hospital discharge
Methodological detailsmulticentre, 9 regional centres
  • Multicentre
  • 9 regional centres

Main finding

As reported in the abstract

Odds ratio

2.73

95% CI 2.17–3.44

By group

Bystander shockvs EMS
OR 2.73 (95% CI 2.17–3.44)

Observational data: associations, not effects.

Secondary outcomes

OutcomeBystander shockEmergency medical servicesAdjusted OR for survival to hospital discharge (95% CI)
Survival to hospital dischargeAdjusted for known predictors of outcome66.5%43.0%2.62 (2.07–3.31)

Benefit of bystander shock by EMS response time

Benefit of bystander shock increased progressively as EMS response time became longer

Original publication

Impact of Bystander Automated External Defibrillator Use on Survival and Functional Outcomes in Shockable Observed Public Cardiac Arrests. Circulation. Published 26 February 2018. doi:10.1161/circulationaha.117.030700

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