Arrhythmias & electrophysiology
Characteristics of Patients With the Arrhythmogenic Mitral Valve Prolapse Syndrome and Sudden Cardiac Arrest and Sustained Ventricular Arrhythmias
Authors' conclusion
In this international descriptive registry of patients with arrhythmogenic mitral valve prolapse syndrome and SCA, patients were young, women, and had bileaflet mitral valve prolapse, mitral annular disjunction, inferolateral T-wave inversions, and nonsustained VT. A history of syncope and anterolateral T-wave inversions was relatively common in patients who survived SCA or sustained VT/ventricular fibrillation.
Study context
- Population
- Patients with arrhythmogenic mitral valve prolapse syndrome who survived sudden cardiac arrest (SCA) or had sustained ventricular tachycardia (VT) or ventricular fibrillationpatients who had SCA or VT/ventricular fibrillation
- Participants
- 148 patients
- Outcome
- Patient characteristics
Methodological detailsinternational
- International
Main finding
As reported in the abstract
- Mean age
- 43.7±15.4 years
- Women
- 68%
- Bileaflet prolapse
- 73%
- Mitral annular disjunction
- 65%
- Nonsustained VT
- 67%
- Inferolateral T-wave inversions
- 59%
- Syncope
- n=54, 48%
- Anterolateral T-wave inversion
- n=26, 22%
Observational data: associations, not effects.
Further findings
Catheter ablation
Patients
- Catheter ablation for premature ventricular complexes
- 50 (35%)
- Catheter ablation for VT
- 18 (17.7%)
Sites of origin for arrhythmias
- Commonly in the papillary muscles, fascicles, mitral annulus, and inferior/inferolateral left ventricle
Original publication
Characteristics of Patients With the Arrhythmogenic Mitral Valve Prolapse Syndrome and Sudden Cardiac Arrest and Sustained Ventricular Arrhythmias. Circ Arrhythm Electrophysiol. Published 20 February 2025. doi:10.
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