Acute cardiac care & resuscitation
Characteristics, therapies, and outcomes of In-Hospital vs Out-of-Hospital cardiac arrest in patients presenting to cardiac intensive care units: From the critical care Cardiology trials network (CCCTN)
Authors' conclusion
Despite a greater burden of comorbidities, CICU admissions after IHCA have lower lactate, greater invasive therapy utilization, and lower crude mortality than admissions after OHCA.
Study context
- Population
- Admissions to tertiary cardiac ICUs (cardiac intensive care unit (CICUs)) in the US and Canada after cardiac arrest
- Participants
- 2,075 admissions · 29 centers
- Exposure
- IHCA vs OHCA
- Outcome
- Mortality (unadjusted)
Methodological detailsmulticenter registry, multicentre, consecutive admissions, 2-month annual snapshots 2017–2021
- Multicenter registry
- Multicentre
- Consecutive admissions
- 2-month annual snapshots 2017–2021
Main finding
As reported in the abstract
CICU mortality
P < 0.001
In-hospital mortality
P < 0.001
Observational data: associations, not effects.
Further findings
Baseline characteristics
Median age IHCA 66 years · OHCA 62 years
Coronary disease
AF
HF
Comatose on CICU arrival
Lactate and therapies
Median lactate IHCA 4.3 · OHCA 5.9
Invasive hemodynamics
Mechanical circulatory support
Renal replacement therapy
Targeted temperature management (comatose patients)
P < 0.001
- Baseline characteristics: p < 0.001 for all
- Lactate and therapies: p < 0.001 for all
Original publication
Characteristics, therapies, and outcomes of In-Hospital vs Out-of-Hospital cardiac arrest in patients presenting to cardiac intensive care units: From the critical care Cardiology trials network (CCCTN). Resuscitation. Published 12 December 2022. doi:10.
Summarised from the published abstract; every number is checked against it