Acute cardiac care & resuscitation

Variation in risk-adjusted cardiac intensive care unit (CICU) length of stay and the association with in-hospital mortality: An analysis from the Critical Care Cardiology Trials Network (CCCTN) registry

Am Heart JPublished Registry-based cohort study

Authors' conclusion

In a large registry of academic CICUs, we observed significant variation in CICU LOS and report that LOS is independently associated with all-cause in-hospital mortality.

Study context

Population
Admissions to 35 academic CICUs in the CCCTN registry, 2017–2022
Participants
22,862 admissions
Exposure
CICU length of stay (LOS) tertiles
Outcome
Inter-hospital differences in CICU LOS and association of CICU LOS with all-cause in-hospital mortality (Fine and Gray competing risk model)
Methodological detailsmulticentre, 35 primarily tertiary and quaternary CICUs, annual 2-month snapshots of consecutive admissions
  • Multicentre
  • 35 primarily tertiary and quaternary CICUs
  • Annual 2-month snapshots of consecutive admissions

Main finding

As reported in the abstract

All-cause in-hospital mortality by CICU LOS tertile
Median CICU LOS, days (IQR)
2.2 (1.1-4.8)
Individual CICU LOS correlated with higher risk of 30-day in-hospital mortality (competing risk analysis)
r2 = 0.31

Observational data: associations, not effects.

Further findings

Hospital LOS

Median hospital LOS, days (IQR)
5.9 (2.8-12.3)

LOS–mortality association in HF, STEMI and NSTEMI admissions (subgroups)

Relationship remained significant

Original publication

Variation in risk-adjusted cardiac intensive care unit (CICU) length of stay and the association with in-hospital mortality: An analysis from the Critical Care Cardiology Trials Network (CCCTN) registry. Am Heart J. Published 16 February 2024. doi:10.1016/j.ahj.2024.02.010

Summarised from the published abstract; every number is checked against it

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