Arrhythmias & electrophysiology
Chasing Conduction Gaps Across the Roof Line: Nearby and Overlap Better Than Appendage Pacing
Authors' conclusion
The longer the activation delay from one side of a line to the other, the greater the chance to unmask a slow conduction gap across the line. Nearby pacing thus better identifies roof line gaps than left appendage pacing. Overlap pacing offers a simple and fast alternative with similar performance.
Study context
- Population
- Patients undergoing atrial fibrillation ablation including a roof line and a floor line
- Participants
- 50 patients
- Comparison
- Pacing modes for roof line validation: left appendage vs nearby vs overlap pacing
- Outcome
- Roof line mapping feasibility
Main finding
As reported in the abstract
Further findings
| Outcome | Left appendage pacing | Nearby pacing | Estimate | P value |
|---|---|---|---|---|
| Sensitivity for true gapsLeft appendage pacing vs nearby pacing · lower with left appendage pacing | sensitivity 48% versus 97% | P < 0.001 | ||
| Sensitivity for true gapsLeft appendage pacing vs overlap pacing · lower with left appendage pacing | sensitivity 48% versus 93% | P < 0.001 | ||
| Negative predictive value for true blockLeft appendage pacing vs nearby pacing · lower with left appendage pacing | negative predictive value 50% versus 94% | P = 0.001 | ||
| Negative predictive value for true blockLeft appendage pacing vs overlap pacing · lower with left appendage pacing | negative predictive value 50% versus 89% | P = 0.004 | ||
| Double potentials durationLeft appendage pacing vs nearby pacing · shorter with left appendage pacing | 63 ± 20 ms | 103 ± 22 ms | P < 0.001 |
Slow conduction gap unmasked only after floor line block
- Patients
- 1
Final box isolation of the dome
- Patients
- 47 (94%)
Original publication
Chasing Conduction Gaps Across the Roof Line: Nearby and Overlap Better Than Appendage Pacing. Circ Arrhythm Electrophysiol. Published 25 July 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →