Coronary disease & ACS

Chest Pain Management Using Prehospital Point-of-Care Troponin and Paramedic Risk Assessment

JAMA Intern MedPublished Economic evaluation

Authors' conclusion

Prehospital point-of-care troponin and paramedic risk stratification for patients with acute chest pain could result in substantial cost savings.

Study context

Population
Adults attended by ambulance with acute chest pain without ST-segment elevation, Victoria, Australia, 2015–2019
Participants
188,551 adults
Comparison
Prehospital point-of-care troponin and paramedic risk stratification vs existing care
Outcome
Estimated mean annualized statewide costs for acute chest pain
Methodological detailscost-minimization analysis, decision tree models, multivariable probabilistic sensitivity analysis, 50 000 Monte Carlo iterations, Prehospital pathway probabilities derived from a literature review
  • Cost-minimization analysis
  • Decision tree models
  • Multivariable probabilistic sensitivity analysis, 50 000 Monte Carlo iterations
  • Prehospital pathway probabilities derived from a literature review

Main finding

As reported in the abstract

Total annual cost vs existing care

Cost savings

6.45 $ million

95% UI 0.59–16.52

Without prehospital discharge · 95% UI; lower in 94.1% of iterations

Cost savings

42.84 $ million

95% UI 19.35–72.26

With prehospital discharge · 95% UI; lower in 100% of iterations

Further findings

OutcomeWithout prehospital dischargeWith prehospital discharge
Annualized infrastructure and staffing costs (5-year device life span)Incl. virtual ED costs for prehospital discharge pathway2.27 $ million4.60 $ million

Original publication

Chest Pain Management Using Prehospital Point-of-Care Troponin and Paramedic Risk Assessment. JAMA Intern Med. Published 1 March 2023. doi:10.1001/jamainternmed.2022.6409

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