Arrhythmias & electrophysiologyCohort study
Chronic right coronary artery changes after cavotricuspid isthmus ablation using a small-basket pentaspline pulsed field catheter: A computed tomography–based assessment
- retrospective analysis
- propensity score-matched analysis
Authors' conclusion
Small-basket PFA for CTI ablation was associated with no major CCTA-detectable progression in the distal RCA in most patients and favorable procedural characteristics compared with RFA. Further prospective studies are needed to confirm long-term safety and efficacy.
Study context
- Population
- Patients who underwent an initial cavotricuspid isthmus (CTI) ablation during atrial fibrillation ablation with paired preablation and approximately 6-month follow-up coronary computed tomographic angiography (CCTA) data from routine clinical carePulsed field ablation (PFA) group 55 · radiofrequency ablation (RFA) group 41
- Participants
- 96 patients
- Exposure
- PFA-based CTI ablation vs radiofrequency ablation
- PFA groupn = 55
- RFA groupn = 41
Main finding
As reported in the abstract
PFA group
98.2%
54 of 55
Observational data: associations, not effects.
Further findings
Coronary Artery Disease Reporting and Data System category, preablation vs follow-up CCTA (PFA group) · approximately 6-month follow-up
- Preablation median [interquartile range]
- 0 [0-1]
- Follow-up median [interquartile range]
- 0 [0-1]
- P
- P = 0.317
- did not significantly change
Minimal luminal area, preablation vs follow-up CCTA (PFA group) · approximately 6-month follow-up
- Preablation median [interquartile range]
- 11.3 [8.4-15.1] mm²
- Follow-up median [interquartile range]
- 11.0 [8.0-15.1] mm²
- P
- P = 0.828
- did not significantly change
Procedural outcomes (procedure time, time to CTI block, first-pass success)
- PFA was associated with a shorter procedure time, shorter time to CTI block, and higher first-pass success
- propensity score-matched analysis
Safety
| Outcome | PFA group | RFA group |
|---|---|---|
| Transient RCA spasm | 1.8% | |
| spasms | Not reported in the abstract | none |
Original publication
Summarised from the published abstract; every number is checked against it