Arrhythmias & electrophysiology
Ablation of cavotricuspid isthmus–dependent atrial flutter using a focal monopolar pulsed-field ablation catheter: Feasibility, periprocedural coronary spasms and conduction disorders
Authors' conclusion
CTI ablation using F-PFA is feasible, but operators should be aware of rare but critical CD and CS during the procedure, even when preventive measures such as nitroglycerin administration are used.
Study context
- Population
- Patients with cavotricuspid isthmus (CTI)-dependent atrial flutter undergoing CTI ablationFocal pulsed-field ablation (F-PFA) 82 · radiofrequency ablation (RFA) 27
- Participants
- 82 vs 27
- Exposure
- F-PFA vs RFA for CTI ablation
- F-PFAn = 82
- RFAn = 27
- Outcome
- First-pass block
Main finding
As reported in the abstract
Observational data: associations, not effects.
Further findings
Procedure time
| Outcome | F-PFA | RFA |
|---|---|---|
| Baseline characteristics | ||
| Mean age | 66 ± 8 years | 63 ± 9 years |
| Female | 15 (18%) | 4 (23%) |
| CHA2DS2-VA score | 1.6 ± 1.3 | 2 ± 1.3 |
Safety
| Outcome | F-PFA | RFA | |
|---|---|---|---|
| Transient ST-segment elevation during ablation | 5% | Not reported in the abstract | RFA: not reported in the abstract |
| Transient complete atrioventricular block during ablation | 2% | Not reported in the abstract | RFA: not reported in the abstract |
PQ interval after CTI ablation
- Small but significant prolongation of the PQ interval in the F-PFA group
Original publication
Ablation of cavotricuspid isthmus–dependent atrial flutter using a focal monopolar pulsed-field ablation catheter: Feasibility, periprocedural coronary spasms and conduction disorders. Heart Rhythm. Published 5 July 2025. doi:10.
Summarised from the published abstract; every number is checked against it