Pulmonary vascular disease & thromboembolism

Cine magnetic resonance imaging detects shorter cardiac rest periods in postcapillary pulmonary hypertension

Eur Heart J Cardiovasc ImagingPublished Cross-sectional study

Authors' conclusion

Postcapillary PH is independently associated with shorter cardiac rest periods at mid-to-late diastole.

Study context

Population
Patients with postcapillary pulmonary hypertension and healthy controls, heart rate ≤80 beats/minute, undergoing cardiac magnetic resonance imaging (MRI)
Participants
26 vs 20
Exposure
Postcapillary pulmonary hypertension (PH) vs healthy controls
  • PHn = 26
  • Controlsn = 20reference
Outcome
Length of cardiac rest periods at end-systole and mid-to-late diastole on cine MRI (four-chamber view)

Main finding

As reported in the abstract

Rest period at mid-to-late diastole

P = 0.003

Observational data: associations, not effects.

Further findings

OutcomeβP value
Postcapillary PH as contributor to shorter rest period at mid-to-late diastole (adjusted for age, sex, heart rate, BP)Adjusted−5.537P = 0.023

Discrimination of PH from controls by proportion of rest period in diastole (diastasis/diastole), ROC

AUC
0.83 (95% CI 0.71-0.96)

Original publication

Cine magnetic resonance imaging detects shorter cardiac rest periods in postcapillary pulmonary hypertension. Eur Heart J Cardiovasc Imaging. Published 20 June 2022. doi:10.1093/ehjci/jeac113

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