Acute cardiac care & resuscitation
Clinical characteristics, management, and predictors of mortality: results from the national prospective cardiogenic shock registry (CZECH-SHOCK)
Authors' conclusion
Acute myocardial infarction complicated by CS still represents the most frequent cause of CS episodes. The in-hospital mortality of patients with CS remains high, despite frequent utilization of haemodynamic support and organ replacement therapies.
Study context
- Population
- Patients with cardiogenic shock (CS) of all aetiologiespatients enrolled
- Participants
- 418 patients
- Outcome
- Baseline characteristics
Methodological details15 main tertiary care centres in Czechia, 12 month period from March 2023 to February 2024
- 15 main tertiary care centres in Czechia
- 12 month period from March 2023 to February 2024
Main finding
As reported in the abstract
Median age, years
70
interquartile range 59–76
Males
69.6%
Newly developed heart failure
76.8%
Acute myocardial infarction complicated by CS as cause of CS episode
56.7%
Observational data: associations, not effects.
Further findings
| Outcome | Estimate | |
|---|---|---|
| Independent factors associated with higher 30 day mortality (multivariate analysis)Age · multivariate analysis | OR 1.78 per 10-year increase (95% CI 1.45–2.19) | |
| Independent factors associated with higher 30 day mortality (multivariate analysis)Society for Cardiovascular Angiography and Interventions class on admission · multivariate analysis | OR 1.64 per one class increase (95% CI 1.27–2.11) | |
| 0.512Odds ratio (log scale) |
Independent factors associated with higher 30 day mortality (multivariate analysis)
| OR (95% CI) | ||
|---|---|---|
| History of coronary artery diseaseMultivariate analysis | 2.38 (1.41–4.30) | |
| History of chronic obstructive pulmonary diseaseMultivariate analysis | 2.58 (1.27–5.25) | |
| Renal replacement therapy during in-hospital stayMultivariate analysis | 2.46 (1.32–4.59) | |
| New mechanical ventilation after admissionMultivariate analysis | 4.58 (2.50–8.39) | |
| 0.10.31310Odds ratio (log scale) |
Use of mechanical circulatory support devices
- Mechanical circulatory support devices utilized
- 28.2%
Mortality · 30 day
- 30 day mortality
- 39.5%
Original publication
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