Arrhythmias & electrophysiology
Clinical features and response at head-up tilt test of patients with situational syncope
Authors' conclusion
Compared with VVS, patients with SS have different clinical characteristics and a higher prevalence of hypotensive drugs leading to hypotensive susceptibility. The positivity rate of HUTT is high and similar to that of VVS, although patients with SS show a higher prevalence of hypotensive responses.
Study context
- Population
- Consecutive patients who underwent nitroglycerin-potentiated head-up tilt test
- Participants
- 1,285 patients
- Exposure
- Situational syncope vs vasovagal syncope
- Outcome
- Clinical characteristics and response at HUTT
Methodological detailsconsecutive patients, nitroglycerin-potentiated head-up tilt test (HUTT)
- Consecutive patients
- Nitroglycerin-potentiated HUTT
Main finding
As reported in the abstract
HUTT positivity
P = 0.9
Observational data: associations, not effects.
Further findings
Male sex
P = 0.001
HUTT response type
Mixed
P = 0.002
Vasodepressor
P = 0.01
Cardioinhibitory
P < 0.0001
| Outcome | SS | VVS | OR | P value |
|---|---|---|---|---|
| Age | 48.8 ± 20.0 | 44.4 ± 19.1 | P = 0.007 | |
| Factors independently associated with SS (multivariable analysis)Smoking habit | 2.28 | P < 0.0001 | ||
| Factors independently associated with SS (multivariable analysis)History of traumatic syncope | 2.29 | P = 0.0001 | ||
| Factors independently associated with SS (multivariable analysis)ACE inhibitors/angiotensin II receptor blockers | 4.74 | P < 0.0001 |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Clinical features and response at head-up tilt test of patients with situational syncope. Heart. Published 1 August 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →