Clinical impact of cardiac magnetic resonance imaging in myocardial infarction with non-obstructive coronary arteries: a prospective multicentre cohort study
Authors' conclusion
CMR in MINOCA is associated with significant changes in clinical diagnosis, diagnostic certainty and management.
Study context
- Population
- Patients with myocardial infarction with non-obstructive coronary arteries (MINOCA)
- Participants
- 320 patients
- Exposure
- Post-CMR vs pre-CMR diagnosis and management
- Outcome
- Composite of:
- Change in clinical diagnosis
- Management after CMR
Methodological detailsmulticentre, international
- Multicentre
- International
Main finding
As reported in the abstract
Change in diagnosis and/or management
Cardiac magnetic resonance (CMR) associated with change in diagnosis and/or management
63%
95% CI 57% to 68%p<0.001
Observational data: associations, not effects.
Secondary outcomes
Diagnostic certainty (/10) · significantly increased certainty
P < 0.0001
Change in diagnosis and/or management, by predictors (early CMR ≤14 days, no atheroma on angiography, pre-CMR certainty ≤5/10)
- All three predictors
- 80%
- None of the predictors
- 40%
- Multivariable logistic regression
Number-needed-to-test by CMR for DAPT deprescription (DAPT initially prescribed despite no obstructive culprit lesion)
- Number-needed-to-test
- 3
Original publication
Clinical impact of cardiac magnetic resonance imaging in myocardial infarction with non-obstructive coronary arteries: a prospective multicentre cohort study. Heart. Published 13 June 2025. doi:10.
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