Coronary disease & ACS

Clinical outcomes and discharge disposition in nonagenarians with ST-elevation myocardial infarction

Am Heart JPublished Prospective cohort study

Authors' conclusion

In this large multicenter prospective STEMI database, nonagenarians living in SNF before presentation had more than 2-fold higher in-hospital mortality than those living at home. Furthermore, patients discharged to SNF had a 3-fold higher 1-year mortality than those discharged to home.

Study context

Population
Patients with ST-elevation myocardial infarction (STEMI) presenting within 24 hours of symptom onset, including advanced age, cardiogenic shock or OHCA; Midwest STEMI Consortium, March 2003–October 2020303 (2%) ≥90 years
Participants
15,039 patients
Exposure
Pre-admission living status and discharge disposition in nonagenarians with STEMI
  • ≥90n = 303
Outcome
Discharge disposition; mortality in-hospital, 30-days and 1-year
Methodological detailsmulticenter, consecutive patients
  • Multicenter
  • Consecutive patients

Main finding

As reported in the abstract

Mortality in nonagenarians
GroupIn-hospital mortality30-day mortality1-year mortality
≥9017%20%33%

≥90

In-hospital mortality17%
30-day mortality20%
1-year mortality33%
In-hospital mortality, living in skilled nursing facility (SNF) before presentation
36%
In-hospital mortality, living at home
14%
In-hospital mortality, living in assisted living facility (ALF)
15%
1-year mortality, discharged to home
13%
1-year mortality, discharged with home health care or ALF
20%
1-year mortality, discharged to SNF (P < .001)
43%

Observational data: associations, not effects.

Original publication

Clinical outcomes and discharge disposition in nonagenarians with ST-elevation myocardial infarction. Am Heart J. Published 27 June 2025. doi:10.1016/j.ahj.2025.06.013

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