The use of healthcare contacts following a first diagnosis of chest pain among women with no obstructive coronary artery disease: results from the WOMANOCA nationwide cohort study
Authors' conclusion
Despite no obstructive CAD, the WOMANOCA cohort had an increased use of new healthcare contacts, indicating a sustained healthcare burden among women with any type of chest pain.
Study context
- Population
- Danish women with a first diagnosis of angina or non-specific chest pain from 2009 to 2019 and no obstructive coronary artery disease (CAD), followed in registries for 3 yearsangina 17,836 · non-specific chest pain 42,832 · references 303,247
- Participants
- 17,836 / 42,832 / 303,247
- Exposure
- Women with angina or non-specific chest pain but no obstructive CAD vs age-matched asymptomatic reference women
- Women with anginan = 17,836
- Women with non-specific chest painn = 42,832reference
- Referencesn = 303,247reference
- Outcome
- All cardiac readmissions
- Follow-up
- 3 years
Methodological detailsmatched to asymptomatic reference women by age, Cox regression models
- Matched to asymptomatic reference women by age
- Cox regression models
Main finding
As reported in the abstract
Hazard ratio (95% CI)
Women with angina vs references
3.24(3.10–3.38)
Women with non-specific chest pain vs references
2.87(2.78–2.97)
Women with angina vs Women with non-specific chest pain
1.16(1.10–1.22)
Observational data: associations, not effects.
Further findings
- Being a woman with non-specific chest pain was significantly associated with GP direct consultations, out-of-hours consultations, and ECGs compared to angina and the reference women
Original publication
The use of healthcare contacts following a first diagnosis of chest pain among women with no obstructive coronary artery disease: results from the WOMANOCA nationwide cohort study. Eur Heart J Qual Care Clin Outcomes. Published 27 June 2025. doi:10.
Summarised from the published abstract; every number is checked against it