Arrhythmias & electrophysiology

Clinical outcomes of Asian patients with newly diagnosed atrial fibrillation and previously diagnosed atrial fibrillation: Insights from the CODE-AF Registry

Heart RhythmPublished Prospective cohort study

Main finding · Composite clinical outcomeResult — go to the resultAdjusted hazard ratio 1.81 95% CI 1.30–2.53

Authors' conclusion

Patients with early-stage AF were younger and had fewer comorbidities. Although there was a higher risk of heart failure admissions and minor bleeding, the risks of death, stroke, and major bleeding were not significantly increased.

Study context

Population
Asian patients with atrial fibrillation (AF) in the CODE-AF registry, enrolled June 2016–March 202122% newly diagnosed
Participants
10,001 patients
Exposure
Newly diagnosed AF vs previously diagnosed AF
Outcome
Composite clinical outcome
Follow-up
Within 90 days
Methodological detailsmulticentre, registry
  • Multicentre
  • Registry

Main finding

As reported in the abstract

Adjusted hazard ratio

1.81

95% CI 1.30–2.53

P < 0.001

Newly diagnosedvs Previously diagnosed
adjusted HR 1.81 (95% CI 1.30–2.53); P < 0.001

Observational data: associations, not effects.

Further findings

All bleeding and HF admission · within 90 days

Higher risk of all bleeding and HF admission in newly diagnosed

Clinical outcomes · 36-month follow-up

No significant differences between groups

Original publication

Clinical outcomes of Asian patients with newly diagnosed atrial fibrillation and previously diagnosed atrial fibrillation: Insights from the CODE-AF Registry. Heart Rhythm. Published 24 October 2024. doi:10.1016/j.hrthm.2024.10.046

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.