Arrhythmias & electrophysiology
Clinical outcomes of Asian patients with newly diagnosed atrial fibrillation and previously diagnosed atrial fibrillation: Insights from the CODE-AF Registry
Main finding · Composite clinical outcomeResult — go to the resultAdjusted hazard ratio 1.81 95% CI 1.30–2.53Authors' conclusion
Patients with early-stage AF were younger and had fewer comorbidities. Although there was a higher risk of heart failure admissions and minor bleeding, the risks of death, stroke, and major bleeding were not significantly increased.
Study context
- Population
- Asian patients with atrial fibrillation (AF) in the CODE-AF registry, enrolled June 2016–March 202122% newly diagnosed
- Participants
- 10,001 patients
- Exposure
- Newly diagnosed AF vs previously diagnosed AF
- Outcome
- Composite clinical outcome
- Follow-up
- Within 90 days
Methodological detailsmulticentre, registry
- Multicentre
- Registry
Main finding
As reported in the abstract
Adjusted hazard ratio
1.81
95% CI 1.30–2.53
P < 0.001
Newly diagnosedvs Previously diagnosed
adjusted HR 1.81 (95% CI 1.30–2.53); P < 0.001
Observational data: associations, not effects.
Further findings
All bleeding and HF admission · within 90 days
- Higher risk of all bleeding and HF admission in newly diagnosed
Clinical outcomes · 36-month follow-up
- No significant differences between groups
Original publication
Clinical outcomes of Asian patients with newly diagnosed atrial fibrillation and previously diagnosed atrial fibrillation: Insights from the CODE-AF Registry. Heart Rhythm. Published 24 October 2024. doi:10. 1016/ j. hrthm. 2024. 10. 046
Composed by AI from the published abstract and checked against it. How Briefs are made →