Arrhythmias & electrophysiology
Clinical Outcomes of Concurrent Ventricular Electrical Storm and Infection
Authors' conclusion
Among patients with ES, those with concurrent infection have increased mortality. Of patients presenting without infection, >5% developed bacteremia after ES, thereby raising the possibility of iatrogenic infection during prolonged hospitalization. Bacteremia and decreased LVEF are independent predictors of mortality.
Study context
- Population
- Patients with ventricular electrical storm (ES), May 2004 to March 2022patients with ES, 68 had concurrent infection, 28 of these with bacteremia
- Participants
- 309 patients
- Comparison
- Infection group vs noninfection group
- Infection groupn = 68
- Outcome
- Pathogen among those with bacteremia
Main finding
As reported in the abstract
Methicillin-resistant Staphylococcus aureus, most common pathogen, among those with bacteremia
9 patients
32.1%
Further findings
| Outcome | P value |
|---|---|
| Mortality · 2-year follow-upSignificantly higher mortality in the infection group | P < 0.001 |
Lead extraction among those with bacteremia
- Lead extraction performed, among those with bacteremia
- 13 (46.4%)
Bacteremia after ES among patients who clearly did not have preceding infection
- Developed bacteremia after ES, among patients without preceding infection
- 15 (5.3%)
Independent predictors of mortality (multivariate logistic regression)
- Bacteremia, OR (95% CI 1.91-15.02; P = 0.001)
- 5.23
- Left ventricular ejection fraction (LVEF), each 1% increase, OR (95% CI: 0.93-0.98; P = 0.002)
- 0.95
- Multivariate logistic regression
Original publication
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