Arrhythmias & electrophysiology
Two-year follow-up of the safety and clinical outcomes of stylet-driven leads for left bundle branch area pacing compared with right ventricular pacing in the Medicare population
Main finding · 30-day acute complicationsResult — go to the resultHazard ratio 1.01Authors' conclusion
DC pacemaker patients with LBBAP using Tendril STS or UltiPace stylet-driven leads experienced significantly lower rates of HFH and all-cause mortality, with similarly low complication rates compared with RVP over 2 years of follow-up in this large Medicare population.
Study context
- Population
- Patients with de novo dual-chamber (DC) pacemaker implants with the Tendril STS or UltiPace leads at left bundle branch area pacing (LBBAP) or right ventricular pacing (RVP) locations, January 1, 2020, to June 30, 2024
- Participants
- 2,341 vs 68,241
- Comparison
- LBBAP vs RVP
- LBBAPn = 2,341
- RVPn = 68,241reference
- Outcome
- 30-day acute complications
- Follow-up
- 30 days
Methodological detailspropensity score overlap weight-adjusted, large real-world data
- Propensity score overlap weight-adjusted
- Large real-world data
Main finding
As reported in the abstract
Hazard ratio
1.01
P = 0.95
Further findings
| Outcome | HR | P value |
|---|---|---|
| Chronic complications · 2 years | 0.92 | P = 0.51 |
| Reinterventions · 2 years | 0.76 | P = 0.06 |
| HFHs · 2 years | 0.72 | P = 0.015 |
| Incident HFHs · 2 years | 0.54 | P = 0.04 |
| All-cause mortality · 2 years | 0.64 | P < 0.0001 |
Original publication
Two-year follow-up of the safety and clinical outcomes of stylet-driven leads for left bundle branch area pacing compared with right ventricular pacing in the Medicare population. Heart Rhythm. Published 9 July 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →