Pulmonary vascular disease & thromboembolism
Clinical relevance and prognostic value of renal Doppler in acute decompensated precapillary pulmonary hypertension
Authors' conclusion
Renal Doppler provides additional information to assess the severity of patients admitted to the intensive care unit for acute decompensated precapillary PH.
Study context
- Population
- Precapillary pulmonary hypertension (PH) patients managed in ICU for acute right HF
- Participants
- 91 patients
- Exposure
- High vs low renal resistance index (RRI) and renal venous stasis index (RVSI) on renal Doppler
- Outcome
- Composite of:
- Death
- Circulatory assistance
- Urgent transplantation
- Rehospitalization for acute right HF
- Follow-up
- 90 days
Main finding
As reported in the abstract
Primary composite endpoint
Primary endpoint event
32 patients
33%
Observational data: associations, not effects.
Further findings
Inotropic support at admission
- More frequently required with high RRI
- P = 0.01
- More frequently required with high RVSI
- P = 0.003
Variables associated with RRI above median (univariate logistic regression)
- Age, history of hypertension, right atrial pressure, renal pulse pressure, tricuspid annular plane systolic excursion (TAPSE), LV outflow tract velocity time integral, systemic pressures, NT-proBNP
Variables associated with RVSI above median
- High central venous pressure, right atrial pressure, renal pulse pressure, TAPSE, severe tricuspid regurgitation, systemic pressures
Original publication
Clinical relevance and prognostic value of renal Doppler in acute decompensated precapillary pulmonary hypertension. Eur Heart J Cardiovasc Imaging. Published 17 May 2023. doi:10.
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