Acute cardiac care & resuscitation

Combinations of First Responder and Drone Delivery to Achieve 5-Minute AED Deployment in Out-of-hospital Cardiac Arrest (OHCA)

JACC AdvPublished Modelling study

Authors' conclusion

Deployment of AEDs by FRs and optimized drone delivery can improve AED arrival times which may lead to improved clinical outcomes.

Study context

Population
OHCA patients ≥18 years in 48 North Carolina counties, CARES registry, 2013–2019
Participants
28,292 patients
Exposure
Automated external defibrillators (AEDs) for all first responder (FRs), then FRs plus optimized drone delivery, vs historical response
Outcome
Response time (9-1-1 call to AED arrival) and proportion of OHCAs with AED arrival <5 minutes
Methodological detailsregistry-based simulation, statewide, 48 North Carolina counties, logistic regression models
  • Registry-based simulation
  • Statewide
  • 48 North Carolina counties
  • Logistic regression models

Main finding

As reported in the abstract

County-level response time and AED arrival <5 minutes
GroupValueAED arrival <5 minutes
Historicalmedian 8.0 (IQR 7.0–9.0) minutes16.5% (IQR: 11.2%-24.3%)
FR AEDsmedian 7.0 (IQR 6.2–7.8) minutes22.3% (IQR: 16.4%-30.9%)
FR AEDs + dronesmedian 4.8 (IQR 4.3–5.2) minutes56.3% (IQR: 46.9%-64.2%)

Value

Historicalmedian 8.0 (IQR 7.0–9.0) minutes
FR AEDsmedian 7.0 (IQR 6.2–7.8) minutes
FR AEDs + dronesmedian 4.8 (IQR 4.3–5.2) minutes

AED arrival <5 minutes

Historical16.5% (IQR: 11.2%-24.3%)
FR AEDs22.3% (IQR: 16.4%-30.9%)
FR AEDs + drones56.3% (IQR: 46.9%-64.2%)

Observational data: associations, not effects.

Further findings

Survival, witnessed OHCAs with estimated drone arrival <5 minutes and ahead of FR and EMS

Estimated increase in survival rates
34%

Original publication

Combinations of First Responder and Drone Delivery to Achieve 5-Minute AED Deployment in OHCA. JACC Adv. Published 25 June 2024. doi:10.1016/j.jacadv.2024.101033

Summarised from the published abstract; every number is checked against it

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