Acute cardiac care & resuscitation

Cost-effectiveness of drone-delivered automated external defibrillators for cardiac arrest

ResuscitationPublished economic evaluation

Authors' conclusion

Drone-delivered AEDs were associated with reductions in response time, mortality and morbidity, and were found to be highly cost-effective relative to standard ambulance response with no drones.

Study context

Population
Out-of-hospital cardiac arrests in Ontario, Canada over 10 years
Participants
22,017 out-of-hospital cardiac arrest (OHCAs)
Comparison
Drone-delivered automated external defibrillators (AEDs) relative to standard ambulance response with no drones
  • Drone networksn = 964
Outcome
Cost-effectiveness of drone networks
Methodological detailscomputational framework combining machine learning, optimization and a Markov microsimulation model
  • Computational framework combining machine learning, optimization and a Markov microsimulation model

Main finding

As reported in the abstract

Networks on the cost-QALY efficient frontier

20

Further findings

OutcomeDrone networksStandard care
Response timeNot reported in the abstractmean 6 min 21 sDrone networks: not reported in the abstract
Survival to hospital dischargeNot reported in the abstract8.4%Drone networks: not reported in the abstract
Response time — Average drone response times shorter than standard care (efficient frontier)
32% to 71%
Survival to hospital discharge — Increase across the 20 drone networks
21% to 46%

Cost per QALY gained, smallest non-dominated drone network (20 drones)

Cost per QALY gained
$20,912

Net monetary benefit

All drone networks had higher net monetary benefit than standard care

Shockable and witnessed populations (subgroups)

Cost-effectiveness was even greater

Sensitivity analyses

Results robust to changes in modelling assumptions

Original publication

Cost-effectiveness of drone-delivered automated external defibrillators for cardiac arrest. Resuscitation. Published 17 February 2025. doi:10.1016/j.resuscitation.2025.110552

Summarised from the published abstract; every number is checked against it

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