Heart failure & cardiomyopathies
Comparison of exercise training modalities and change in peak oxygen consumption in heart failure with preserved ejection fraction: a secondary analysis of the OptimEx-Clin trial
Primary result · Change in peak V̇O2Result — go to the resultMean difference −0.1 %Authors' conclusion
In HFpEF, isocaloric HIIT and MCT seem to be equally effective over 3 months.
Study context
- Population
- Patients with heart failure with preserved ejection fraction (HFpEF) undergoing 3 months of exercise training
- Comparison
- MCT vs high-intensity interval training (HIIT)
- Primary endpoint
- Associations of ET frequency, duration, intensity (%HRR) and estimated energy expenditure with change in peak V̇O2
- Follow-up
- 3 months
Primary result
Change in peak V̇O2
Mean difference
−0.1 %
P = 0.98
Change by group
MCT
9.2
SD 13.2 · %
HIIT
8.7
SD 15.9 · %
As reported in the abstract
- Peak V̇O2 change positively associated with exercise training (ET) frequency, MCT
- R2 = 0.103
- Peak V̇O2 change positively associated with ET frequency, HIIT
- R2 = 0.149
- Peak V̇O2 change positively associated with ET duration/week, MCT
- R2 = 0.120
- Peak V̇O2 change positively associated with ET duration/week, HIIT
- R2 = 0.125
- Average %HRR negatively associated with peak V̇O2 change, MCT (P = 0.034)
- R2 = 0.101
- No significant association of %HRR with peak V̇O2 change, HIIT
- P = 0.234
Original publication
Comparison of exercise training modalities and change in peak oxygen consumption in heart failure with preserved ejection fraction: a secondary analysis of the OptimEx-Clin trial. Eur J Prev Cardiol. Published 25 October 2024. doi:10.
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