Valvular & structural heart disease
Comparison of Incidence, Prevalence and Death of Aortic Stenosis and Aortic Insufficiency in a Nationwide Korean Study
Authors' conclusion
Over 70% of AVD patients were age ≥ 60 years. The 10 year SR of AS, ASAR and RAS exhibited similar patterns, all of which were lower than the SR for other AVD. AVD portends a worse prognosis in older individuals, males, those with lower income levels and those with comorbidities.
Study context
- Population
- Patients with newly diagnosed non-rheumatic and rheumatic aortic valve disorders (AVD, ICD-10: I35 and I06), excluding congenital heart disease, National Health Insurance Service in Korea, 2006 through 2017newly diagnosed AVD, female: male = 6:4
- Participants
- 101,895 patients
- Comparison
- Epidemiology of aortic stenosis (AS), AR, ASAR, RAS, RAR and RASAR
- Outcome
- Distribution of AVD types
Main finding
As reported in the abstract
- Among all AVD, AR had the highest distribution
Further findings
| Outcome | Values |
|---|---|
| 10 year survival rates (SR)SR of AS, ASAR and RAS were lower than those for AR and RAR | AS 49.2% · ASAR 50.2% · RAS 51.4% · AR 64.5% · RAR 69.2% |
Age of AVD patients
- AVD patients age ≥ 60 years
- More than 70%
Age-standardized incidence and prevalence · over the decade
- Non-rheumatic AVD: incidence remained stable, prevalence increased
- Rheumatic AVD: both incidence and prevalence decreased
Adjusted hazard ratio for AVD (risk factors)
- Higher in individuals who were older, male, had a lower income level, diabetes mellitus, myocardial infarction, heart failure, atrial fibrillation, stroke, chronic kidney disease or malignant neoplasms
Original publication
Comparison of Incidence, Prevalence and Death of Aortic Stenosis and Aortic Insufficiency in a Nationwide Korean Study. ESC Heart Fail. Published 24 February 2025. doi:10.
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