Valvular & structural heart disease
Relationship between cardiac implantable electronic devices and tricuspid regurgitation in the general population
Authors' conclusion
Patients with a CIED experienced a higher risk of TR and tricuspid interventions, although the magnitude of the hazard was smaller than other cardiovascular risk factors.
Study context
- Population
- Adults who received care in an emergency department, hospital, or outpatient surgery facility in California from 1 October 2015 to 31 December 2020, excluding patients with rheumatic or congenital heart disease, endocarditis, and carcinoidpatients contributing 54,650,137 person-years
- Participants
- 16,889,936 adults
- Exposure
- Cardiac implantable electronic devices (CIED) implantation vs no CIED
- Outcome
- Incident TR
- Follow-up
- Median of 3.55 years
Main finding
As reported in the abstract
Instances of tricuspid regurgitation (TR)
10,757
Unadjusted: CIED implantation associated with higher risk of incident TR
17-fold
Adjusted for demographics and medical comorbidities: higher risk of TR with a CIED
65%
Observational data: associations, not effects.
Further findings
- Tricuspid valve interventions identified
- 72
- After multivariable adjustment: CIED implantation associated with increased risk of tricuspid intervention
- 3-fold
Original publication
Relationship between cardiac implantable electronic devices and tricuspid regurgitation in the general population. Heart Rhythm. Published 24 July 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →