Heart failure & cardiomyopathies
Comparison of Supine and Sitting Pulmonary Pressures in Ambulatory Heart Failure Patients Using the Novel Cordella Pulmonary Pressure System
Authors' conclusion
This study presents the largest paired comparison of supine and sitting PAP and demonstrates a high degree of correlation between seated and supine measures of PAP.
Study context
- Population
- NYHA class III heart failure (HF) patients with the Cordella pulmonary artery pressure (PAP) sensor40,115 paired measurements
- Participants
- 504 patients
- Comparison
- Supine vs seated PAP
- Primary endpoint
- Relationship between supine and seated PAP measurements
Methodological detailspaired measurements
- Paired measurements
Primary result
As reported in the abstract
mPAP, sPAP, dPAP
Difference
7.1 ± 6.5 mmHg
P < 0.001
mPAP; correlation = 0.85
Difference
9.0 ± 8.5 mmHg
P < 0.001
sPAP; correlation = 0.88
Difference
5.2 ± 5.6 mmHg
P < 0.001
dPAP; correlation = 0.82
Supine
- mPAP
- 29.1 ± 11.6
- sPAP
- 44.4 ± 16.6
- dPAP
- 19.1 ± 9.5
Seated
- mPAP
- 22.1 ± 12.2
- sPAP
- 35.4 ± 17.8
- dPAP
- 13.9 ± 9.5
mPAP
Supine29.1 ± 11.6
Seated22.1 ± 12.2
sPAP
Supine44.4 ± 16.6
Seated35.4 ± 17.8
dPAP
Supine19.1 ± 9.5
Seated13.9 ± 9.5
Further findings
Supine-seated difference by mPAP quartile
- Differences larger at lower mPAP, narrowed at higher pressures
- P < 0.001
Seated mPAP trends before HF hospitalization
- Modest increases prior to HF hospitalization
Original publication
Comparison of Supine and Sitting Pulmonary Pressures in Ambulatory Heart Failure Patients Using the Novel Cordella Pulmonary Pressure System. ESC Heart Fail. Published 17 July 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →