Acute cardiac care & resuscitation
Comparison of ventilation modes in non-traumatic out-of-hospital cardiac arrest: SYMEVECA phase 2
Authors' conclusion
Successful resuscitation may vary according to ventilation mode - the use of a mechanical ventilation and different modes such as CCSV requires further study.
Study context
- Population
- Adults with non-traumatic out-of-hospital cardiac arrest attended by an emergency medical service between April-2021 and September-2024cardiac arrests recorded, 252 excluded (very early recovery 193, airway difficulty 54, protocol violations 5) · CCSV 100 · IPPV 145 · resuscitator bag 276
- Participants
- 773 adults
- Exposure
- Ventilation method during CPR: CCSV vs IPPV vs manual resuscitator bag
- CCSVn = 100
- IPPVn = 145
- Resuscitator bagn = 276
- Outcome
- Survival at hospital discharge or 28 days with good neurological recovery (CPC 1-2)
- Follow-up
- Hospital discharge or 28 days
Main finding
As reported in the abstract
P = 0.07
Observational data: associations, not effects.
Further findings
pCO2 · 15 min after tracheal intubation or when spontaneous circulation was achieved
Spontaneous circulation achieved
Mean
| Outcome | CCSV | IPPV | Resuscitator bag |
|---|---|---|---|
| Venous pH · 15 min after tracheal intubation or when spontaneous circulation was achievedPatients with a venous control sample | 7.01 (SD 0.15) | 7.00 (SD 0.14) | 6.96 (SD 0.15) |
- Venous pH: p = 0.02
- pCO2: p = 0.13
- Spontaneous circulation achieved: p = 0.08
Original publication
Comparison of ventilation modes in non-traumatic out-of-hospital cardiac arrest: SYMEVECA phase 2. Resuscitation. Published 21 May 2025. doi:10.
Summarised from the published abstract; every number is checked against it