Acute cardiac care & resuscitation
Ventilatory improvement with mechanical ventilator versus bag in non-traumatic out-of-hospital cardiac arrest: SYMEVECA study, phase 1
Authors' conclusion
The use of a mechanical ventilator in IPPV was associated with a better ventilatory status during CPR compared to the use of the bag, without conclusive data regarding its clinical repercussion with the sample collected.
Study context
- Population
- Adults (>18 years) with non-traumatic OHCA attended by an emergency medical service, April 2021–September 2022of 359 attended
- Participants
- 150 adults
- Exposure
- Mechanical ventilator vs manual resuscitator bag during CPR
- IPPVn = 71
- Bagn = 79reference
- Outcome
- Gasometry parameters and final outcome
- Follow-up
- 15 minutes after intubation or at return of spontaneous circulation; to hospital discharge
Methodological detailspragmatic, out-of-hospital urban environment
- Pragmatic
- Out-of-hospital urban environment
Main finding
As reported in the abstract
Values
Arterial pH IPPV 7.00 ± 0.18 · Bag 6.92 ± 0.18 · P = 0.18
Venous pCO2 IPPV 68.1 ± 18.9 mmHg · Bag 89.5 ± 26.5 mmHg · P < 0.001
Venous pH IPPV 7.03 ± 0.15 · Bag 6.94 ± 0.17 · P = 0.005
Survival with CPC 1-2 to hospital discharge IPPV 15.6% · Bag 11.3% · P = 0.44
- IPPV vs Bag: P = 0.006 — arterial pCO2
Observational data: associations, not effects.
Original publication
Ventilatory improvement with mechanical ventilator versus bag in non-traumatic out-of-hospital cardiac arrest: SYMEVECA study, phase 1. Resuscitation. Published 12 September 2023. doi:10. 1016/ j. resuscitation. 2023. 109965
Summarised from the published abstract; every number is checked against it