Acute cardiac care & resuscitation

Ventilatory improvement with mechanical ventilator versus bag in non-traumatic out-of-hospital cardiac arrest: SYMEVECA study, phase 1

ResuscitationPublished Prospective quasi-experimental study

Authors' conclusion

The use of a mechanical ventilator in IPPV was associated with a better ventilatory status during CPR compared to the use of the bag, without conclusive data regarding its clinical repercussion with the sample collected.

Study context

Population
Adults (>18 years) with non-traumatic OHCA attended by an emergency medical service, April 2021–September 2022of 359 attended
Participants
150 adults
Exposure
Mechanical ventilator vs manual resuscitator bag during CPR
  • IPPVn = 71
  • Bagn = 79reference
Outcome
Gasometry parameters and final outcome
Follow-up
15 minutes after intubation or at return of spontaneous circulation; to hospital discharge
Methodological detailspragmatic, out-of-hospital urban environment
  • Pragmatic
  • Out-of-hospital urban environment

Main finding

As reported in the abstract

Values

Arterial pH IPPV 7.00 ± 0.18 · Bag 6.92 ± 0.18 · P = 0.18

Venous pCO2 IPPV 68.1 ± 18.9 mmHg · Bag 89.5 ± 26.5 mmHg · P < 0.001

Venous pH IPPV 7.03 ± 0.15 · Bag 6.94 ± 0.17 · P = 0.005

Survival with CPC 1-2 to hospital discharge IPPV 15.6% · Bag 11.3% · P = 0.44

  • IPPV vs Bag: P = 0.006 — arterial pCO2

Observational data: associations, not effects.

Original publication

Ventilatory improvement with mechanical ventilator versus bag in non-traumatic out-of-hospital cardiac arrest: SYMEVECA study, phase 1. Resuscitation. Published 12 September 2023. doi:10.1016/j.resuscitation.2023.109965

Summarised from the published abstract; every number is checked against it

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