Valvular & structural heart diseaseCohort study

Comprehensive Aortic Stenosis Characterization Using Multiview Deep Learning

JACC Cardiovasc ImagingPublication date not resolved

  • Cohort study
  • Trained on 210,193 images from 16,076 studies from KPNC

Authors' conclusion

EchoNet-AS synthesizes information from both B-mode videos and Doppler images to accurately assess AS severity. Its strong performance generalizes robustly to external validation cohorts and shows potential as an automated clinical decision support tool.

Study context

Population
Echocardiographic studies to assess AS severity16,076 training studies
Outcome
Discrimination of severe AS (AUC)

Main finding

As reported in the abstract

Discrimination of severe AS (EchoNet-AS)

AUC, KPNC held-out cohort

0.964 (95% CI: 0.952-0.973)

AUC, KPNC temporally distinct cohort

0.986 (0.983-0.989)

AUC, SHC external cohort

0.985 (0.975-0.992)

AUC, CSMC external cohort

0.989 (0.986-0.992)

Observational data: associations, not effects.

Original publication

Comprehensive Aortic Stenosis Characterization Using Multiview Deep Learning. JACC Cardiovasc Imaging. doi:10.1016/j.jcmg.2026.07.013

Summarised from the published abstract; every number is checked against it