Acute cardiac care & resuscitation
Computed tomography grey-white matter ratio at the basal ganglia level in a reference population for hypoxic ischaemic encephalopathy after cardiac arrest – A cross-sectional observational study
Authors' conclusion
A GWR at the basal ganglia level below 1.10 is very unlikely in elderly patients without HIE, suggesting that this may provide a relevant cut-off for HIE prognostication in cardiac arrest patients.
Study context
- Population
- Patients with computed tomography (CT) for suspected stroke or transient ischaemic attack, matched on age and sex to cardiac arrest populations, without pathologic CT findingsparticipants included
- Participants
- 155 patients
- Outcome
- GWR < 1.10
Main finding
As reported in the abstract
- No measurement resulted in GWR < 1.10
Observational data: associations, not effects.
Further findings
Median GWR for all raters
- 0.1 cm² regions of interest (ROIs)
- 1.30-1.32
- 0.2 cm² ROIs
- 1.27-1.32
Interrater limits of agreement
- Lower and upper limits of agreement between raters
- around 0.1
- 0.2 cm² ROIs GWR achieved smaller limits of agreement compared to the 0.1 cm² ROIs GWR
Attenuation measurements and GWR by ROI size
- Attenuation measurements and GWR differed depending on ROI size used
Participant characteristics
- Mean age
- 75 years
- Male
- 59 %
Original publication
Computed tomography grey-white matter ratio at the basal ganglia level in a reference population for hypoxic ischaemic encephalopathy after cardiac arrest – A cross-sectional observational study. Resuscitation. Published 4 July 2025. doi:10.
Summarised from the published abstract; every number is checked against it