Acute cardiac care & resuscitation
Prognostic performance of gray-white matter ratio in adult out-of-hospital cardiac arrest patients after receiving extracorporeal cardiopulmonary resuscitation
Authors' conclusion
Early neuro-prognostication depending on GWR may not be sufficient after ECPR
Study context
- Population
- Adults with out-of-hospital cardiac arrest (OHCA) treated with extracorporeal cardiopulmonary resuscitation (ECPR)
- Participants
- 1,146 adults
- Comparison
- Lower average GWR (aGWR) categories vs aGWR 1.30-1.39
- Primary endpoint
- Poor neurological outcome
- Follow-up
- 30 days
Methodological detailsretrospective cohort study, multicenter
- Retrospective cohort study
- Multicenter
Primary result
As reported in the abstract
Each group vs aGWR 1.30-1.39Adjusted odds ratio (95% CI)
aGWR 1.00-1.09
10.01(3.58–27.99)
aGWR 1.10-1.19
4.83(2.31–10.12)
aGWR 1.20-1.29
2.16(1.02–4.55)
Further findings
Prognostic performance of aGWR for poor neurological outcome (ROC)
- AUC
- 0.628 (95% CI 0.59-0.66)
- Threshold 1.005: specificity
- 100%
- Threshold 1.005: sensitivity
- 0.1%
Original publication
Prognostic performance of gray-white matter ratio in adult out-of-hospital cardiac arrest patients after receiving extracorporeal cardiopulmonary resuscitation. Resuscitation. Published 3 August 2024. doi:10.
Summarised from the published abstract; every number is checked against it