Coronary disease & ACS

Computed Tomography Radiomics Model Predicts Procedure Success of Coronary Chronic Total Occlusions

Circ Cardiovasc ImagingPublished Diagnostic accuracy study

Authors' conclusion

CT radiomics-based model outperformed CT-derived Multicenter CTO Registry of Japan score for predicting PCI success.

Study context

Population
Patients with coronary chronic total occlusion (CTO) undergoing percutaneous coronary intervention (PCI)training 202, internal validation 98, external test 75
Comparison
Computed tomography (CT) radiomics model vs CT-derived J-CTO score for predicting PCI success
Outcome
Prediction of PCI (revascularization) success
Methodological detailsretrospective, 2 tertiary hospitals, external test set
  • Retrospective
  • 2 tertiary hospitals
  • External test set

Performance

As reported in the abstract

Prediction of PCI success (external test set, 83 CTO lesions)
Test or modelAUCAccurately identified CTO lesions with procedure success
CT radiomics model0.92089.16% (74/83)
CT-derived J-CTO score0.752

AUC

CT radiomics model0.920
CT-derived J-CTO score0.752

Accurately identified CTO lesions with procedure success

CT radiomics model89.16% (74/83)
CT-derived J-CTO score— not stated in the abstract
  • CT radiomics model vs CT-derived J-CTO score: P = 0.008 — 0.920 vs 0.752

Further findings

Occlusion length, PCI success vs PCI failure (external test set)

P = 0.007

Tortuous course, PCI success vs PCI failure (external test set)

P = 0.004

OutcomePCI successPCI failureP value
Radiomics score, PCI success vs PCI failure (external test set)0.100.55P < 0.001

Original publication

Computed Tomography Radiomics Model Predicts Procedure Success of Coronary Chronic Total Occlusions. Circ Cardiovasc Imaging. Published 21 February 2023. doi:10.1161/circimaging.122.014826

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