Arrhythmias & electrophysiology

Computerized clinical decision support to improve stroke prevention therapy in primary care management of atrial fibrillation: a cluster randomized trial

Am Heart JPublished Cluster randomised controlled trial

Primary result · Managed according to guidelinesResult — go to the resultRelative risk 1.08 95% CI 1.01–1.15

Authors' conclusion

Notwithstanding high baseline rates, primary care provider access to the CDS over 12 months further optimized the prescribing of OAC therapy per national guidelines to AF patients potentially eligible to receive it.

Study context

Population
Patients with atrial fibrillation (AF) managed in primary care (providers with high-speed Internet), Nova Scotia203 primary care providers
Participants
1,145 patients
Comparison
Computerized clinical decision support (CDS) vs usual care
  • CDSn = 590
  • Usual care (UC)n = 543reference
Primary endpoint
Patients managed with guideline-based OAC therapy
Follow-up
12 months
Methodological detailsprimary care practices across Nova Scotia, Recruitment June 14, 2014 to December 15, 2016; 12-month follow-up
  • Primary care practices across Nova Scotia
  • Recruitment June 14, 2014 to December 15, 2016; 12-month follow-up

Primary result

Managed according to guidelines

Relative risk

1.08

95% CI 1.01–1.15

P = 0.024

Events by treatment group

CDS vs UC
RR 1.08 (95% CI 1.01–1.15); P = 0.024

As reported in the abstract

Further findings

OutcomeCDSUCRR (95% CI)P value
Guideline-based OAC therapy at baseline74.9%68.7%0.97 (0.87–1.07)P = 0.511

Original publication

Computerized clinical decision support to improve stroke prevention therapy in primary care management of atrial fibrillation: a cluster randomized trial. Am Heart J. Published 28 April 2024. doi:10.1016/j.ahj.2024.04.016

Summarised from the published abstract; every number is checked against it

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