Arrhythmias & electrophysiology

Continuous Rhythm Monitoring With Implanted Loop Recorders in Children and Adolescents With Brugada Syndrome

J Am Coll CardiolPublished Multicentre cohort study

Authors' conclusion

Continuous rhythm monitoring with ILRs in young patients with BrS detects a broad range of arrhythmias. Ventricular arrhythmias occur predominantly in patients with spontaneous type 1 electrocardiograms and during fever. Despite the young age, bradyarrhythmias and atrial arrhythmias are frequent and represent the cause of arrhythmic syncope in 60% of patients.

Study context

Population
Children and adolescents (<18 years) with Brugada syndrome with an implantable loop recorder
Participants
147 children
Exposure
Pediatric vs Adolescents
  • Pediatricn = 77
  • Adolescentsn = 70
Outcome
Arrhythmia prevalence during continuous implantable loop recorder (ILR) monitoring
Follow-up
Median 3.6 years (Q1-Q3: 1.6-4.8 years)
Methodological details12 international centres
  • 12 international centres

Main finding

As reported in the abstract

Arrhythmic events · median follow-up 3.6 years

Any arrhythmic event

33

22.4%

Atrial events

15

10.2%

Bradyarrhythmic events

16

10.9%

Ventricular arrhythmias (all with spontaneous Brugada syndrome (BrS); fever-related in one-half)

4

Observational data: associations, not effects.

Further findings

Cause of recurrent syncope during follow-up

True arrhythmic syncope documented
5 (17.8%)
Due to bradyarrhythmias or atrial arrhythmias
3 cases (60%)

Original publication

Continuous Rhythm Monitoring With Implanted Loop Recorders in Children and Adolescents With Brugada Syndrome. J Am Coll Cardiol. Published 3 September 2024. doi:10.1016/j.jacc.2024.04.070

Summarised from the published abstract; every number is checked against it

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