Coronary disease & ACS

Coronary computed tomography angiography versus invasive coronary angiography for interventional triage in acute coronary syndrome: Design of the randomized TRACTION trial

Am Heart JPublished Design of a randomised controlled trial

Study context

Population
Patients hospitalised with NSTEMI or unstable angina with ischaemic ECG changes (non-ST elevation acute coronary syndrome (NSTE-ACS))planned enrolment
Participants
2,300 patients
Planned comparison
Coronary computed tomography angiography (CCTA) vs invasive coronary angiography (ICA) for interventional triage
Primary endpoint
MACE: all-cause mortality, nonfatal MI, hospitalisation for refractory angina or for HF
Follow-up
1 year
Methodological detailsTRACTION, multicentre, open-label, non-inferiority, 1:1 randomisation
  • TRACTION
  • Multicentre
  • Open-label
  • Non-inferiority
  • 1:1 randomisation

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Coronary computed tomography angiography versus invasive coronary angiography for interventional triage in acute coronary syndrome: Design of the randomized TRACTION trial. Am Heart J. Published 6 December 2025. doi:10.1016/j.ahj.2025.107325

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