Cardio-oncology & other

Cost-effectiveness analysis of a cardio-oncology rehabilitation framework compared to an exercise intervention for cancer survivors with high cardiovascular risk

Eur J Prev CardiolPublished Secondary analysis of the CORE randomised trial

Authors' conclusion

The CORE trial shows that CBCR is a cost-effective intervention in the management of cancer survivors with high cardiovascular risk

Study context

Population
Adult cancer survivors with previous cardiotoxic cancer treatment and/or previous CVD (high CV risk)75 completed
Participants
80 survivors
Comparison
Centre-based cardiac rehabilitation (CBCR) vs community-based exercise training (CBET)
  • CBCRn = 38
  • CBETn = 37reference
Primary endpoint
Cost-effectiveness (healthcare resource use and costs, QALYs, ICER from a societal perspective)
Methodological detailssingle-centre, prospective, pre-specified secondary endpoint, cost-effectiveness analysis, societal perspective
  • Single-centre
  • Prospective
  • Pre-specified secondary endpoint
  • Cost-effectiveness analysis
  • Societal perspective

Primary result

As reported in the abstract

CBCR vs CBETDifference, € (95% CI)P value
Cost per patient
138.44(116.82–160.05)
P < 0.01
Favouring CBCR
difference 0.100 quality-adjusted life-years (QALYs) (95% CI −0.163 to −0.037); P = 0.002
CBCR
Incremental cost-effectiveness ratio (ICER) 1383.24 € per QALY gained
Probability CBCR cost-effective at WTP €5000 per QALY
99.9% (95% CI, 99.4-100.0)

Original publication

Cost-effectiveness analysis of a cardio-oncology rehabilitation framework compared to an exercise intervention for cancer survivors with high cardiovascular risk. Eur J Prev Cardiol. Published 24 May 2024. doi:10.1093/eurjpc/zwae181

Composed by AI from the published abstract and checked against it. How Briefs are made →

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