Cost-effectiveness of Mediterranean diet and physical activity in secondary cardiovascular disease prevention: results from the UCC-SMART cohort study
Main finding · Cost-effectiveness (healthcare perspective, lifetime horizon)Result — go to the resultICER −626 €/QALY 95% CI −1929 to 2673Authors' conclusion
In patients with established CVD, a combined Mediterranean diet and physical activity intervention was cost-saving and highly cost-effective compared with usual care.
Study context
- Population
- Patients with established cardiovascular disease (CVD) (UCC-SMART cohort, n = 8947, mean age 62 ± 8.7 years, 74% male)simulated cohort from n = 8947
- Participants
- 100,000 patients
- Exposure
- Combined Mediterranean diet and physical activity intervention vs usual care
- Outcome
- Cost-effectiveness: ICER, incremental net health benefit (INHB) and incremental net monetary benefit (INMB)
- Follow-up
- Lifetime horizon
Methodological detailshealthcare perspective, lifetime horizon
- Healthcare perspective
- Lifetime horizon
Main finding
As reported in the abstract
Cost-effectiveness (healthcare perspective, lifetime horizon)
Incremental cost-effectiveness ratio (ICER)
−626 €/QALY
95% CI −1929 to 2673
- Incremental net health benefit (INHB) at willingness-to-pay of €20 000/QALY
- 2.04 quality-adjusted life years (QALYs) (95% CI 0.99-3.58)
- Incremental net monetary benefit (INMB) at willingness-to-pay of €20 000/QALY (95% CI 19 819-71 605)
- €40 757
Observational data: associations, not effects.
Further findings
- Remained cost-effective in a wide range of sensitivity analyses, incl. worst-case scenarios and reimbursement of food and physical activity costs
Original publication
Cost-effectiveness of Mediterranean diet and physical activity in secondary cardiovascular disease prevention: results from the UCC-SMART cohort study. Eur J Prev Cardiol. Published 28 March 2024. doi:10.
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