Acute cardiac care & resuscitation
DanGer Shock-Like Profile Predicts the Outcome in ST-Elevation Myocardial Infarction-Related Cardiogenic Shock
Main finding · All-cause mortalityResult — go to the resultHazard ratio 0.57 95% CI 0.39–0.83Authors' conclusion
A DGS-like profile was associated with a lower 180-day mortality compared with a DGS-unlike profile in a STEMI-CS cohort treated by mAFP.
Study context
- Population
- Patients with STEMI-related cardiogenic shock (STEMI-CS) receiving a microaxial flow pump (mAFP), in an all-comers cardiogenic shock registrySTEMI-CS patients, of a registry including 478 CS-patients
- Participants
- 225 patients
- Exposure
- DanGer Shock (DGS)-like vs DGS-unlike STEMI-CS patients treated by mAFP
- DGS-liken = 64
- Outcome
- All-cause mortality
- Follow-up
- 180 days
Main finding
As reported in the abstract
Hazard ratio
0.57
95% CI 0.39–0.83
By group
DGS-like vs DGS-unlike
HR 0.57 (95% CI 0.39–0.83)
Observational data: associations, not effects.
Further findings
All-cause mortality · 30 days
P < 0.001
| Outcome | HR (95% CI) | |
|---|---|---|
| All-cause mortality · 30 daysMultivariable analysis | 0.48 (0.32–0.72) | |
| 0.20.5125Hazard ratio (log scale) |
Baseline characteristics
- DGS-like patients were younger, had less often received CPR before mAFP implantation, and mAFP-support was longer
- Comorbidities, baseline lactate, coronary artery disease characteristics/treatment, inotropes/vasopressors, and escalation to other mechanical circulatory support devices were not different
Original publication
DanGer Shock-Like Profile Predicts the Outcome in ST-Elevation Myocardial Infarction-Related Cardiogenic Shock. ESC Heart Fail. Published 19 March 2025. doi:10.
Summarised from the published abstract; every number is checked against it