Arrhythmias & electrophysiology
Deep sedation protocol during atrial fibrillation ablation using a novel variable-loop biphasic pulsed field ablation catheter
Authors' conclusion
During PFA ablation procedures with the variable-loop circular catheter and its accompanying biphasic pulse, our deep sedation protocol is a valid alternative to general anesthesia.
Study context
- Population
- Patients undergoing pulsed field ablation (PFA) for paroxysmal atrial fibrillation (AF) in the inspIRE trial
- Participants
- 29 patients
- Outcome
- Sedation and analgesia scores
- Follow-up
- During procedure
Main finding
As reported in the abstract
- Richmond Agitation-Sedation Scale (RASS) −1 to −5
- 27 (93%)
- RASS 0
- 2 (7%)
- Visual Analogue Scale (VAS) 0 to 2
- 24 (83%)
- VAS 3
- 3 (10%)
- VAS 4
- 2 (7%)
- PSI <50
- 16 (55%)
- PSI 50 to 70
- 9 (31%)
Safety
Procedural complications, need for non-invasive ventilation or intubation
- Procedural complications
- 0
- Non-invasive ventilation or tracheal intubation required
- 0
- Sufficient oxygen saturation maintained in all patients
Original publication
Deep sedation protocol during atrial fibrillation ablation using a novel variable-loop biphasic pulsed field ablation catheter. Europace. Published 20 July 2023. doi:10.
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