Acute cardiac care & resuscitationRandomised controlled trial
Deferring Arterial Catheterization in Critically Ill Patients with Shock
- Randomised controlled trial
- multicentre
- open-label
- non-inferiority
Authors' conclusion
Among patients with shock, results for death from any cause at day 28 indicated that management without early arterial catheter insertion was noninferior to early catheter insertion.
Study context
- Population
- Patients with shock admitted to an ICU within the past 24 hours
- Participants
- 504 vs 502
- Comparison
- Noninvasive BP monitoring vs early arterial catheter insertion
- Noninvasive strategyn = 504
- Invasive strategyn = 502reference
- Primary endpoint
- Death from any cause (non-inferiority margin 5 percentage points)
- Follow-up
- Day 28
Primary result
Death from any cause · 28 days
Adjusted risk difference
−3.2 percentage points
95% CI −8.9 to 2.5
P = 0.006 for non-inferiority
Events by treatment group
As reported in the abstract
Further findings
Arterial catheter insertion
Safety
≥1 day of pain or discomfort related to the BP-monitoring device
Hematoma or hemorrhage related to the arterial catheter
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Summarised from the published abstract; every number is checked against it