Heart failure & cardiomyopathies
Delta QRS and outcomes post cardiac resynchronization therapy (CRT) in the Resynchronization-Defibrillation for Ambulatory Heart Failure Trial
Primary resultResult — go to the resultHazard ratio 1.012 95% CI 1.008–1.017Authors' conclusion
For patients receiving CRT for heart failure with left ventricular systolic dysfunction and QRS prolongation, ΔQRSd was an independent predictor of long-term mortality and heart failure hospitalization.
Study context
- Population
- Patients with LV systolic dysfunction and prolonged QRS who received CRT in RAFT, with ECGs at baseline and after implantationRAFT randomized 1798
- Participants
- 813 patients
- Comparison
- ΔQRSd after CRT as predictor of outcomes
- ΔQRSd ≤0n = 447
- Primary endpoint
- Composite of:
- Death
- HF hospitalization
Primary result
As reported in the abstract
Hazard ratio
1.012
95% CI 1.008–1.017
ΔQRSd
HR 1.012 (95% CI 1.008–1.017)
Further findings
ΔQRSd distribution · after implantation
- Median ΔQRSd
- −2 ms (−20 to 18 ms)
- ΔQRSd ≤0
- 447 (55%)
Original publication
Delta QRS and outcomes post CRT in the Resynchronization-Defibrillation for Ambulatory Heart Failure Trial. Heart Rhythm. Published 10 October 2024. doi:10. 1016/ j. hrthm. 2024. 10. 011
Composed by AI from the published abstract and checked against it. How Briefs are made →