Valvular & structural heart disease
Determinants of post-operative left ventricular dysfunction in degenerative mitral regurgitation
Authors' conclusion
Post-operative LV impairment is common. Indexed LV volumes (36.3 mL/m2) provided the best marker of post-operative LV impairment.
Study context
- Population
- Patients with mitral valve prolapse undergoing mitral valve surgery
- Participants
- 87 patients
- Outcome
- Post-operative LV impairment (LVEF < 50%)
- Follow-up
- 1 year post-surgery
Main finding
As reported in the abstract
Post-operative LV impairment
- Incidence of post-operative left ventricular (LV) impairment
- 13%
- LVESVi, independent predictor (multivariate): OR 1.11 (95% CI 1.01-1.23)
- P = 0.039
- Global longitudinal strain (GLS), independent predictor (multivariate): OR 1.46 (95% CI 1.00-2.14)
- P = 0.054
- LVESVi optimal cut-off 36.3 mL/m²: sensitivity
- 82%
- LVESVi optimal cut-off 36.3 mL/m²: specificity
- 78%
Observational data: associations, not effects.
Further findings
Pre-operative LV measures, patients with vs without post-operative LV dysfunction
- Significantly larger indexed LV end-systolic diameters and LVESVi, lower LVEF and more abnormal GLS with post-operative LV dysfunction
Original publication
Determinants of post-operative left ventricular dysfunction in degenerative mitral regurgitation. Eur Heart J Cardiovasc Imaging. Published 4 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →