Heart failure & cardiomyopathies
Developing a Multilevel Polypill Implementation Bundle for Patients With Heart Failure With Reduced Ejection Fraction
Authors' conclusion
This study illustrates the development of a multilevel HFrEF polypill implementation bundle that can be further tailored to improve HFrEF care in undertreated populations globally.
Study context
- Population
- Patients with Heart Failure with Reduced Ejection Fraction (HFrEF) and providers, Washington University in St. Louis and University of California-San Francisco, April–December 2023
- Participants
- 9 vs 22
- Comparison
- patient vs provider
- patientn = 9
- providern = 22
Methodological detailsconvergent parallel, multicentre
- Convergent parallel
- Multicentre
Main finding
As reported in the abstract
Themes affecting implementation of a polypill-based approach to HFrEF
Four themes identified; current state of HFrEF care the organizing theme, influenced by awareness of new innovations, assessing innovation appropriateness and building competency in HFrEF care
4
Multilevel HFrEF polypill implementation bundle developed
7 domains
Original publication
Developing a Multilevel Polypill Implementation Bundle for Patients With Heart Failure With Reduced Ejection Fraction. JACC Adv. Published 8 October 2025. doi:10.
Summarised from the published abstract; every number is checked against it