Prevention & lipids

Development and validation of cardiovascular risk prediction equations in 76 000 people with known cardiovascular disease

Eur J Prev CardiolPublished Prognostic model development and validation study

Authors' conclusion

Robust cardiovascular risk prediction equations were developed from linked routine health databases, a currently underutilized resource worldwide.

Study context

Population
People aged 18–84 years with known cardiovascular disease (CVD), living in Auckland and Northland, Aotearoa New Zealand, on 1 January 2014
Participants
43,862 vs 32,724
Comparison
Men vs Women
  • Menn = 43,862
  • Womenn = 32,724
Outcome
Death or hospitalization due to ischaemic heart disease, stroke, HF or peripheral vascular disease
Follow-up
5 years
Methodological detailslinked administrative health databases cohort, sex-specific equations, multivariable Fine and Gray models, Follow-up until study outcome, death, or 5 years
  • Linked administrative health databases cohort
  • Sex-specific equations
  • Multivariable Fine and Gray models
  • Follow-up until study outcome, death, or 5 years

Performance

As reported in the abstract

CV events and predicted 5-year CV risk

Predicted 5-year CV risk <15%

Predicted 5-year CV risk ≥40%

Original publication

Development and validation of cardiovascular risk prediction equations in 76 000 people with known cardiovascular disease. Eur J Prev Cardiol. Published 28 September 2023. doi:10.1093/eurjpc/zwad314

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