Valvular & structural heart disease
Device-Related Findings on Computed Tomography After Transcatheter Pulmonary Valve Replacement With the Harmony Valve
Authors' conclusion
This study provides novel data related to hypoattenuated leaflet thickening, tissue ingrowth within the TPV frame, and proximity of the implanted valve to the coronary arteries
Study context
- Population
- Patients after transcatheter pulmonary valve replacement with the Harmony valve who had a postimplant CT angiogram36 with CT angiogram
- Participants
- 63 patients
- Outcome
- Device-related findings on postimplant CT angiogram
- Follow-up
- 0.2 to 4.9 years (median 1 year) after implant
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Hypoattenuated leaflet thickening
28%
Tissue ingrowth/thickening on the luminal aspect of the device
39%
Observational data: associations, not effects.
Further findings
Hypoattenuated leaflet thickening after addition of oral anticoagulants · 6 months later
- Reversed in patients with a second follow-up CT angiogram
- 2
- Most patients discharged on aspirin without anticoagulation
Original publication
Device-Related Findings on Computed Tomography After Transcatheter Pulmonary Valve Replacement With the Harmony Valve. Circ Cardiovasc Interv. Published 17 September 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →