Diabetes mellitus and presentation, care and outcomes of patients with NSTEMI: the Association for Acute Cardiovascular Care-European Association of Percutaneous Cardiovascular Interventions EURObservational Research Programme NSTEMI Registry of the European Society of Cardiology
Authors' conclusion
NSTEMI patients with diabetes, compared with those without, present more clinically unwell and have worse outcomes despite receiving equal quality of care.
Study context
- Population
- Patients admitted to hospital with NSTEMI (ESC EURObservational NSTEMI Registry)
- Participants
- 2,928 patients
- Exposure
- Diabetes vs no diabetes
- Diabetesn = 1,104
- No diabetesn = 1,824reference
- Outcome
- In-hospital acute HF, cardiogenic shock, repeat MI, stroke/TIA, BARC type ≥3 bleeding and death; 30-day mortality
Methodological detailsmulticentre, 287 centres in 59 countries
- Multicentre
- 287 centres in 59 countries
Main finding
As reported in the abstract
In-hospital outcomes and 30-day mortality
In-hospital acute HF
P < 0.001
Cardiogenic shock
P = 0.002
Stroke/TIA
P = 0.006
In-hospital death
P = 0.022
30-day mortality
P = 0.025
Observational data: associations, not effects.
Further findings
Presentation
Killip class II–IV HF
Haemodynamic instability
Ongoing chest pain
Quality of care (received ≥80% of eligible care interventions)
P = 0.786
- Discharge therapy and referral (diabetes)
- 1.9% · GLP-1 receptor agonist · SGLT2 inhibitor 9.0% · Cardiac rehabilitation referral 45.9%
- Presentation: all P < 0.001
Original publication
Diabetes mellitus and presentation, care and outcomes of patients with NSTEMI: the Association for Acute Cardiovascular Care-European Association of Percutaneous Cardiovascular Interventions EURObservational Research Programme NSTEMI Registry of the European Society of Cardiology. Eur Heart J Qual Care Clin Outcomes. Published 8 January 2024. doi:10.
Summarised from the published abstract; every number is checked against it